Endocrine Abstracts

Background: Hypocaloric diets reduce the risk for type 2 diabetes (T2D) in obese subjects. However, there is a large inter-subject variability in the response to these interventions. The factors affecting this variability remain poorly understood. We and others reported that high plasma apoB-lipoproteins predict risk factors for, and incidence of, T2D in obese subjects independent of adiposity or fat distribution.Objective: To test the hypothesis that pl...